The immunomodulatory effect of acupuncture in improving insomnia is mainly reflected in the following aspects:

Enhancing immune system function: Acupuncture, by stimulating specific acupoints, can enhance the function of the immune system and improve the body’s disease resistance. Studies show that acupuncture can stimulate specific meridians, enhance the production of white blood cells and immunoglobulins, and thereby strengthen the immune response. This immunomodulatory effect helps prevent colds and other immune-related diseases, and indirectly improves insomnia caused by weakened immunity.
Regulating inflammatory responses: Acupuncture can alleviate inflammatory responses and relieve insomnia caused by immune dysfunction. Inflammatory responses are closely related to sleep quality. Excessive inflammatory responses can interfere with the sleep cycle. Acupuncture improves sleep quality by regulating the immune system and reducing the release of inflammatory mediators.
Promoting the balance of the neuro-endocrine-immune system: Acupuncture restores the body’s homeostasis by regulating the neuro-endocrine-immune system. Insomnia is often related to the imbalance of the neuro-endocrine-immune system. Acupuncture can regulate the functions of these systems and promote their mutual coordination, thereby improving the symptoms of insomnia.
Reduce psychological stress and improve immune status: Insomniacs often have psychological problems such as anxiety and depression, which can further affect the immune status. Acupuncture improves the immune status by regulating the nervous system, alleviating anxiety and stress, and promoting physical relaxation. For instance, acupuncture can promote the secretion of pleasure-inducing hormones such as endorphins, alleviate psychological stress, and indirectly enhance the immune function.